(E)-N'-Arylidene-2-(4-oxoquinazolin-4(3H)-yl) acetohydrazides: Synthesis and evaluation of antitumor cytotoxicity and caspase activation activity

In our search for novel small molecules activating procaspase-3, we have designed and synthesised a series of novel acetohydrazides incorporating quinazolin-4(3H)-ones (5, 6, 7). Biological evaluation revealed eight compounds with significant cytotoxicity against three human cancer cell lines (SW620...

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Main Authors: Le Cong Huan (Author), Cao Viet Phuong (Author), Le Cong Truc (Author), Vo Nguyen Thanh (Author), Hai Pham-The (Author), Le- (Author), Nguyen Thi Thuan (Author), Eun Jae Park (Author), A Young Ji (Author), Jong Soon Kang (Author), Sang-Bae Han (Author), Phuong-Thao Tran (Author), Nguyen-Hai Nam (Author)
Format: Book
Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
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Call Number: A1234.567
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