Effects of Montelukast on Arsenic-Induced Epithelial-Mesenchymal Transition and the Role of Reactive Oxygen Species Production in Human Bronchial Epithelial Cells

• मुख्य लेखकों: Huang-Chi Chen (लेखक), Hsin-Ying Clair Chiou (लेखक), Mei-Lan Tsai (लेखक), Szu-Chia Chen (लेखक), Ming-Hong Lin (लेखक), Tzu-Chun Chuang (लेखक), Chih-Hsing Hung (लेखक), Chao-Hung Kuo (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2022-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Background: Epithelial-mesenchymal transition (EMT) of airway lung epithelial cells is considered a major driver of fibrosis and airway remodeling. Arsenic exposure is well known to cause the malignant transformation of cells, including those in the lung. Accumulating studies have shown that arsenic...