Effects of Montelukast on Arsenic-Induced Epithelial-Mesenchymal Transition and the Role of Reactive Oxygen Species Production in Human Bronchial Epithelial Cells

• Main Authors: Huang-Chi Chen (Author), Hsin-Ying Clair Chiou (Author), Mei-Lan Tsai (Author), Szu-Chia Chen (Author), Ming-Hong Lin (Author), Tzu-Chun Chuang (Author), Chih-Hsing Hung (Author), Chao-Hung Kuo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Epithelial-mesenchymal transition (EMT) of airway lung epithelial cells is considered a major driver of fibrosis and airway remodeling. Arsenic exposure is well known to cause the malignant transformation of cells, including those in the lung. Accumulating studies have shown that arsenic...