CoQ10 Augments Rosuvastatin Neuroprotective Effect in a Model of Global Ischemia via Inhibition of NF-κB/JNK3/Bax and Activation of Akt/FOXO3A/Bim Cues

• Auteurs principaux: Sarah A. Abd El-Aal (Auteur), Mai A. Abd El-Fattah (Auteur), Hanan S. El-Abhar (Auteur)
• Format: Livre
• Publié: Frontiers Media S.A., 2017-10-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Statins were reported to lower the Coenzyme Q10 (CoQ10) content upon their inhibition of HMG-CoA reductase enzyme and both are known to possess neuroprotective potentials; therefore, the aim is to assess the possible use of CoQ10 as an adds-on therapy to rosuvastatin to improve its effect using glob...