CoQ10 Augments Rosuvastatin Neuroprotective Effect in a Model of Global Ischemia via Inhibition of NF-κB/JNK3/Bax and Activation of Akt/FOXO3A/Bim Cues

Statins were reported to lower the Coenzyme Q10 (CoQ10) content upon their inhibition of HMG-CoA reductase enzyme and both are known to possess neuroprotective potentials; therefore, the aim is to assess the possible use of CoQ10 as an adds-on therapy to rosuvastatin to improve its effect using glob...

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Autores principales: Sarah A. Abd El-Aal (Autor), Mai A. Abd El-Fattah (Autor), Hanan S. El-Abhar (Autor)
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Publicado: Frontiers Media S.A., 2017-10-01T00:00:00Z.
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