<i>BRAF</i> and <i>MLH1</i> Analysis Algorithm for the Evaluation of Lynch Syndrome Risk in Colorectal Carcinoma Patients: Evidence-Based Data from the Analysis of 100 Consecutive Cases

• Váldodahkkit: Thais Maloberti (Dahkki), Antonio De Leo (Dahkki), Viviana Sanza (Dahkki), Lidia Merlo (Dahkki), Michela Visani (Dahkki), Giorgia Acquaviva (Dahkki), Sara Coluccelli (Dahkki), Annalisa Altimari (Dahkki), Elisa Gruppioni (Dahkki), Stefano Zagnoni (Dahkki), Daniela Turchetti (Dahkki), Sara Miccoli (Dahkki), Michelangelo Fiorentino (Dahkki), Antonietta D'Errico (Dahkki), Dario de Biase (Dahkki), Giovanni Tallini (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: MDPI AG, 2022-06-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Several causes may lead to CRC, either extrinsic (sporadic forms) or genetic (hereditary forms), such as Lynch syndrome (LS). Most sporadic deficient mismatch repair (dMMR) CRC cases are characterized by the methylation of the <i>MLH1</i> promoter gene and/or <i>BRAF</i> gene...