Medicinal chemistry advances in targeting class I histone deacetylases

Medicinal chemistry advances in targeting class I histone deacetylases

Histone deacetylases (HDACs) are a class of zinc (Zn)-dependent metalloenzymes that are responsible for epigenetic modifications. HDACs are largely associated with histone proteins that regulate gene expression at the DNA level. This tight regulation is controlled by acetylation [via histone acetyl...

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Main Authors: Diaaeldin I. Abdallah (Author), Elvin D. de Araujo (Author), Naman H. Patel (Author), Lina S. Hasan (Author), Richard Moriggl (Author), Oliver H. Krämer (Author), Patrick T. Gunning (Author)
Format: Book
Published: Open Exploration Publishing Inc., 2023-08-01T00:00:00Z.
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3rd Floor Main Library

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