Protocatechuic aldehyde attenuates cisplatin-induced acute kidney injury by suppressing Nox-mediated oxidative stress and renal inflammation

• Main Authors: Li Gao (Author), weifeng Wu (Author), guiling Ren (Author), haidi Li (Author), qin Yang (Author), xiaofeng Li (Author), tao Xu (Author), zeng Li (Author), baoming Wu (Author), taotao Ma (Author), cheng Huang (Author), dong Lei (Author), yan Hang (Author), lei Zhang (Author), xiongwen Lv (Author), Jun Li (Author), Xiaoming Meng (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cisplatin is a classic chemotherapeutic agent widely used to treat different types of cancers including ovarian, head and neck, testicular and uterine cervical carcinomas. However, cisplatin induces acute kidney injury by directly triggering an excessive inflammatory response, oxidative stress and p...