Dipeptide-modified nanoparticles to facilitate oral docetaxel delivery: new insights into PepT1-mediated targeting strategy

• Główni autorzy: Yuqian Du (Autor), Chutong Tian (Autor), Menglin Wang (Autor), Di Huang (Autor), Wei Wei (Autor), Yan Liu (Autor), Lin Li (Autor), Bingjun Sun (Autor), Longfa Kou (Autor), Qiming Kan (Autor), Kexin Liu (Autor), Cong Luo (Autor), Jin Sun (Autor), Zhonggui He (Autor)
• Format: Książka
• Wydane: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Oligopeptide transporter 1 (PepT1) has been a striking prodrug-designing target. However, the underlying mechanism of PepT1 as a target to facilitate the oral absorption of nanoparticles (NPs) remains unclear. Herein, we modify Poly (lactic-co-glycolic acid) (PLGA) NPs with the conjugates of dipepti...