Identification of transcriptome characteristics of granulosa cells and the possible role of UBE2C in the pathogenesis of premature ovarian insufficiency

• Main Authors: Dan Liu (Author), Xiaohong Guan (Author), Wenqiang Liu (Author), Yanping Jia (Author), Hong Zhou (Author), Chenxiang Xi (Author), Mei Zhao (Author), Yuan Fang (Author), Li Wu (Author), Kunming Li (Author)
• Format: Book
• Published: BMC, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Premature ovarian insufficiency (POI) is an important cause of infertility characterized by the functional decline of the ovary. Granulosa cells (GCs) around oocytes are critical for folliculogenesis, and GC dysfunction is one of the important etiologies of POI. The aim of this s...