Development of an Optimized LC-MS Method for the Detection of Specialized Pro-Resolving Mediators in Biological Samples

• Main Authors: Laura Kutzner (Author), Katharina M. Rund (Author), Annika I. Ostermann (Author), Nicole M. Hartung (Author), Jean-Marie Galano (Author), Laurence Balas (Author), Thierry Durand (Author), Michael S. Balzer (Author), Sascha David (Author), Nils Helge Schebb (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The cardioprotective and anti-inflammatory effects of long chain omega-3 polyunsaturated fatty acids (n3 PUFA) are believed to be partly mediated by their oxygenated metabolites (oxylipins). In the last two decades interest in a novel group of autacoids termed specialized pro-resolving mediators (SP...