Metformin Increases Survival in Hypopharyngeal Cancer Patients with Diabetes Mellitus: Retrospective Cohort Study and Cell-Based Analysis

• Main Authors: Yung-An Tsou (Author), Wei-Chao Chang (Author), Chia-Der Lin (Author), Ro-Lin Chang (Author), Ming-Hsui Tsai (Author), Liang-Chun Shih (Author), Theresa Staniczek (Author), Tsu-Fang Wu (Author), Hui-Ying Hsu (Author), Wen-Dien Chang (Author), Chih-Ho Lai (Author), Chuan-Mu Chen (Author)
• Format: Book
• Published: MDPI AG, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hypopharyngeal squamous cell carcinoma (HSCC) is usually diagnosed at an advanced stage, leading to a poor prognosis. Even after improvement of surgical techniques, chemotherapy, and radiation technology, the survival rate of HSCC remains poor. Metformin, which is commonly used for type 2 diabetes m...