Identification of Trim24 as a new NTRK3 fusion partner in lung adenocarcinoma: Diagnostic challenges of a novel fusion

• Main Authors: Almudena Santón (Author), Eugenia Olmedo (Author), Tamara Caniego-Casas (Author), Amparo Benito (Author), Mónica García-Cosío (Author), Jorge Esteban-Villarrubia (Author), Pilar Garrido (Author), José Palacios (Author)
• Format: Book
• Published: Elsevier, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Reliable neurotrophin kinase (NTRK) fusion assessment is of special relevance since durable responses to targeted therapies have been observed regardless tumor type, NTRK gene or fusion partner. The most prevalent NTRK fusion in solid tumors is the ETV6-NTRK3, although alternative NTRK3 translocatio...