ApoE-Targeting Increases the Transfer of Solid Lipid Nanoparticles with Donepezil Cargo across a Culture Model of the Blood-Brain Barrier

• Main Authors: Gizem Rüya Topal (Author), Mária Mészáros (Author), Gergő Porkoláb (Author), Anikó Szecskó (Author), Tamás Ferenc Polgár (Author), László Siklós (Author), Mária A. Deli (Author), Szilvia Veszelka (Author), Asuman Bozkir (Author)
• Format: Book
• Published: MDPI AG, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pharmacological treatment of central nervous system (CNS) disorders is difficult, because the blood-brain barrier (BBB) restricts the penetration of many drugs into the brain. To solve this unmet therapeutic need, nanosized drug carriers are the focus of research efforts to develop drug delivery sys...