Natural Product Erianin Inhibits Bladder Cancer Cell Growth by Inducing Ferroptosis via NRF2 Inactivation

• Main Authors: Yu Xiang (Author), Xiaying Chen (Author), Wengang Wang (Author), Lijuan Zhai (Author), Xueni Sun (Author), Jiao Feng (Author), Ting Duan (Author), Mingming Zhang (Author), Ting Pan (Author), Lili Yan (Author), Ting Jin (Author), Quan Gao (Author), Chengyong Wen (Author), Weirui Ma (Author), Wencheng Liu (Author), Deqiang Wang (Author), Qibiao Wu (Author), Tian Xie (Author), Xinbing Sui (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Erianin, a natural product derived from Dendrobium chrysotoxum Lindl, has been proved to play antitumor activity in various cancers. However, the effects and molecular mechanisms of erianin in bladder cancer cells remain unexplored. In this study, we found that erianin triggered cell death and cell...