Comparison of Different Liquid Chromatography-Based Purification Strategies for Adeno-Associated Virus Vectors

• Main Authors: Ruth Rieser (Author), Johanna Koch (Author), Greta Faccioli (Author), Klaus Richter (Author), Tim Menzen (Author), Martin Biel (Author), Gerhard Winter (Author), Stylianos Michalakis (Author)
• Format: Book
• Published: MDPI AG, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Recombinant adeno-associated virus (rAAV) vectors have evolved as one of the most promising technologies for gene therapy due to their good safety profile, high transduction efficacy, and long-term gene expression in nondividing cells. rAAV-based gene therapy holds great promise for treating genetic...