The Therapeutic and Diagnostic Potential of Phospholipase C Zeta, Oocyte Activation, and Calcium in Treating Human Infertility

• Main Authors: Haia M. R. Abdulsamad (Author), Zoha F. Murtaza (Author), Hessa M. AlMuhairi (Author), Wjdan S. Bafleh (Author), Salma A. AlMansoori (Author), Shaikha A. AlQubaisi (Author), Hamdan Hamdan (Author), Junaid Kashir (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Oocyte activation, a fundamental event during mammalian fertilisation, is initiated by concerted intracellular patterns of calcium (Ca²⁺) release, termed Ca²⁺ oscillations, predominantly driven by testis-specific phospholipase C zeta (PLCζ). Ca<sup>...