Single-cell RNA sequencing identifies a subtype of FN1 + tumor-associated macrophages associated with glioma recurrence and as a biomarker for immunotherapy

• Main Authors: Houshi Xu (Author), Huihui Chai (Author), Ming Chen (Author), Ruize Zhu (Author), Shan Jiang (Author), Xiaoyu Liu (Author), Yue Wang (Author), Jiawen Chen (Author), Junji Wei (Author), Ying Mao (Author), Zhifeng Shi (Author)
• Format: Book
• Published: BMC, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Glioma is the most common primary malignant tumor in the brain, and even with standard treatments including surgical resection, radiotherapy, and chemotherapy, the long-term survival rate of patients remains unsatisfactory. Recurrence is one of the leading causes of death in glio...