Modeling the Probability of HIV Infection over Time in High-Risk Seronegative Participants Receiving Placebo in Five Randomized Double-Blind Placebo-Controlled HIV Pre-Exposure Prophylaxis Trials: A Patient-Level Pooled Analysis

• Main Authors: Maria Garcia-Cremades (Author), Craig W. Hendrix (Author), Priya Jayachandran (Author), Natasha Strydom (Author), Leah Jarlsberg (Author), Robert Grant (Author), Connie L. Celum (Author), Michael Martin (Author), Jared M. Baeten (Author), Jeanne Marrazzo (Author), Peter Anderson (Author), Kachit Choopanya (Author), Suphak Vanichseni (Author), David V. Glidden (Author), Radojka M. Savic (Author)
• Format: Book
• Published: MDPI AG, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The World Health Organization recommends pre-exposure prophylaxis (PrEP) for individuals at substantial risk of HIV infection. The aim of this analysis is to quantify the individual risk of HIV infection over time, using a large database of high-risk individuals (<i>n</i> = 5583). We use...