Inhibiting glycosphingolipids alleviates cardiac hypertrophy by reducing reactive oxygen species and restoring autophagic homeostasis

• Main Authors: Chunxin Jiang (Author), Menglei Tan (Author), Lunmeng Lai (Author), Yanping Wang (Author), Zijun Chen (Author), Qing Xie (Author), Yunsen Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

IntroductionCardiac hypertrophy is a compensatory stress response produced by a variety of factors, and pathologic hypertrophy can lead to irreversible, severe cardiac disease. Glycosphingolipids (GSLs) are vital constituents of cells, and changes in their content and composition are important facto...