Fast Green FCF Alleviates Pain Hypersensitivity and Down-Regulates the Levels of Spinal P2X4 Expression and Pro-inflammatory Cytokines in a Rodent Inflammatory Pain Model

• Main Authors: Fang Xu (Author), Jing Yang (Author), Fan Lu (Author), Rongjun Liu (Author), Jinwei Zheng (Author), Junfang Zhang (Author), Wei Cui (Author), Chuang Wang (Author), Wenhua Zhou (Author), Qinwen Wang (Author), Xiaowei Chen (Author), Junping Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Fast Green FCF (FGF), a biocompatible dye, recently drew attention as a potential drug to treat amyloid-deposit diseases due to its effects against amyloid fibrillogenesis in vitro and a high degree of safety. However, its role in inflammatory pain is unknown. Our study aimed to investigate the effe...