Novel 3,4-Dihydroisocoumarins Inhibit Human P-gp and BCRP in Multidrug Resistant Tumors and Demonstrate Substrate Inhibition of Yeast Pdr5

Multidrug resistance (MDR) in tumors and pathogens remains a major problem in the efficacious treatment of patients by reduction of therapy options and subsequent treatment failure. Various mechanisms are described to be involved in the development of MDR with overexpression of ATP-binding cassette...

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Main Authors: Julia Sachs (Author), Katja Döhl (Author), Anja Weber (Author), Michele Bonus (Author), Ferdinand Ehlers (Author), Edmond Fleischer (Author), Anette Klinger (Author), Holger Gohlke (Author), Jörg Pietruszka (Author), Lutz Schmitt (Author), Nicole Teusch (Author)
Format: Book
Published: Frontiers Media S.A., 2019-04-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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