Novel 3,4-Dihydroisocoumarins Inhibit Human P-gp and BCRP in Multidrug Resistant Tumors and Demonstrate Substrate Inhibition of Yeast Pdr5
Multidrug resistance (MDR) in tumors and pathogens remains a major problem in the efficacious treatment of patients by reduction of therapy options and subsequent treatment failure. Various mechanisms are described to be involved in the development of MDR with overexpression of ATP-binding cassette...
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Main Authors: | , , , , , , , , , , |
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Format: | Book |
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Frontiers Media S.A.,
2019-04-01T00:00:00Z.
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A1234.567 |
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Copy 1 | Available |