Effects of renal function on pharmacokinetics and pharmacodynamics of lesinurad in adult volunteers

• Hlavní autoři: Gillen M (Autor), Valdez S (Autor), Zhou D (Autor), Kerr B (Autor), Lee CA (Autor), Shen Z (Autor)
• Médium: Kniha
• Vydáno: Dove Medical Press, 2016-11-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Michael Gillen,1 Shakti Valdez,2 Dongmei Zhou,2 Bradley Kerr,2 Caroline A Lee,2 Zancong Shen2 1AstraZeneca LP, Gaithersburg, MD, 2Ardea Biosciences, Inc., San Diego, CA, USA Introduction: Lesinurad is a selective uric acid reabsorption inhibitor approved for the treatment of gout in combination with...