Developmental Changes in Action Potential Prolongation by K+-Channel Blockers in Chick Myocardium

• Main Authors: Hideaki Nouchi (Author), Naoaki Kiryu (Author), Mikio Kimata (Author), Yayoi Tsuneoka (Author), Shogo Hamaguchi (Author), Iyuki Namekata (Author), Akira Takahara (Author), Koki Shigenobu (Author), Hikaru Tanaka (Author)
• Format: Book
• Published: Elsevier, 2011-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The effects of K+-channel blockers on the action potential duration of the myocardium were examined in isolated right ventricles from the 7 - 10-day-old, 11 - 13-day-old, and 14 - 20-day-old embryo and 1 - 7-day-old hatched chicks. E-4031 significantly prolonged action potential duration at all deve...