The Glp-1 Analog Liraglutide Protects Against Angiotensin II and Pressure Overload-Induced Cardiac Hypertrophy via PI3K/Akt1 and AMPKa Signaling

• Main Authors: Ran Li (Author), Yingguang Shan (Author), Lu Gao (Author), Xi Wang (Author), Xule Wang (Author), Fang Wang (Author)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2019-06-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

The Glp-1 analog, liraglutide (Lir), has been shown to reduce infarct size and improve cardiac function after myocardial ischemia in rodents with or without diabetes. However, the effect of Lir on angiotensin II (AngII) and pressure overload induced cardiac hypertrophy in nondiabetic mice and the un...