Pharmaceutical and pharmacokinetic evaluation of a newly formulated multiparticulate matrix of levodopa and carbidopa

• Main Authors: Emelia Priscilla Imbeah (Author), Ofosua Adi-Dako (Author), Benoit N'guessan (Author), Kennedy Kwami Edem Kukuia (Author), Benedicta Obenewaa Dankyi (Author), Ismaila Adams (Author), Ebenezer Ofori-Attah (Author), Regina Appiah-Opong (Author), Seth Kwabena Amponsah (Author)
• Format: Book
• Published: International Association of Physical Chemists (IAPC), 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Levodopa is routinely co-administered with carbidopa in the management of Parkinson's disease. Although the aforementioned combination therapy is effective, there may be fluctuating plasma levels of levodopa after oral administration. We formulated and evaluated the kinetic characteristics of t...