Hybrid Silica-Coated PLGA Nanoparticles for Enhanced Enzyme-Based Therapeutics

• मुख्य लेखकों: Kyle T. Gustafson (लेखक), Negin Mokhtari (लेखक), Elise C. Manalo (लेखक), Jose Montoya Mira (लेखक), Austin Gower (लेखक), Ya-San Yeh (लेखक), Mukanth Vaidyanathan (लेखक), Sadik C. Esener (लेखक), Jared M. Fischer (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Some cancer cells rely heavily on non-essential biomolecules for survival, growth, and proliferation. Enzyme based therapeutics can eliminate these biomolecules, thus specifically targeting neoplastic cells; however, enzyme therapeutics are susceptible to immune clearance, exhibit short half-lives,...