Emergence of ceftazidime-avibactam resistance due to a novel blaKPC-2 mutation during treatment of carbapenem-resistant Klebsiella pneumoniae infections

• Hoofdauteurs: Quanfeng Liao (Auteur), Jin Deng (Auteur), Yu Feng (Auteur), Weili Zhang (Auteur), Siying Wu (Auteur), Ya Liu (Auteur), Huijuan Che (Auteur), Yi Xie (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2022-05-01T00:00:00Z.
• Onderwerpen: article
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Objective: Klebsiella pneumoniae carbapenemase (KPC)-producing K.pneumoniae has represented a serious health problem in worldwide. The resistance to ceftazidime-avibactam (CAZ-AVI) began to emerge since its approval in 2015. We aim to explore the resistance mechanism of CAZ-AVI. Methods: Phenotypic...