Emergence of ceftazidime-avibactam resistance due to a novel blaKPC-2 mutation during treatment of carbapenem-resistant Klebsiella pneumoniae infections

• المؤلفون الرئيسيون: Quanfeng Liao (مؤلف), Jin Deng (مؤلف), Yu Feng (مؤلف), Weili Zhang (مؤلف), Siying Wu (مؤلف), Ya Liu (مؤلف), Huijuan Che (مؤلف), Yi Xie (مؤلف)
• التنسيق: كتاب
• منشور في: Elsevier, 2022-05-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Objective: Klebsiella pneumoniae carbapenemase (KPC)-producing K.pneumoniae has represented a serious health problem in worldwide. The resistance to ceftazidime-avibactam (CAZ-AVI) began to emerge since its approval in 2015. We aim to explore the resistance mechanism of CAZ-AVI. Methods: Phenotypic...