Mechanism of the Cardioprotective Effects of Docetaxel Pre-administration Against Adriamycin-Induced Cardiotoxicity

• Autors principals: Mari Tomonari (Autor), Hideto To (Autor), Motohiro Nishida (Autor), Takashi Mishima (Autor), Hitoshi Sasaki (Autor), Hitoshi Kurose (Autor)
• Format: Llibre
• Publicat: Elsevier, 2011-01-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

We revealed that pre-treatment with docetaxel (DOC) 12 h before adriamycin (ADR) administration significantly reduced ADR-induced toxic death compared with the simultaneous dosing schedule that was commonly used in previous studies. We considered that pre-treatment with DOC relieves ADR-induced card...