PolyADP-Ribosylation of NFATc3 and NF-κB Transcription Factors Modulate Macrophage Inflammatory Gene Expression in LPS-Induced Acute Lung Injury

• Main Authors: Yunjuan Nie (Author), Teja Srinivas Nirujogi (Author), Ravi Ranjan (Author), Brenda F. Reader (Author), Sangwoon Chung (Author), Megan N. Ballinger (Author), Joshua A. Englert (Author), John W. Christman (Author), Manjula Karpurapu (Author)
• Format: Book
• Published: Karger Publishers, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pulmonary macrophages play a critical role in the recognition of pathogens, initiation of host defense via inflammation, clearance of pathogens from the airways, and resolution of inflammation. Recently, we have shown a pivotal role for the nuclear factor of activated T-cell cytoplasmic member 3 (NF...