Stimulator of interferon genes promotes diabetic sarcopenia by targeting peroxisome proliferator activated receptors γ degradation and inhibiting fatty acid oxidation

• Main Authors: Sen‐bo Yan (Author), Huan Liang (Author), Peng Zhan (Author), Hui Zheng (Author), Qin‐xiao Zhao (Author), Zi‐jie Zheng (Author), Hui‐xia Lu (Author), Guo‐kai Shang (Author), Xiao‐ping Ji (Author)
• Format: Book
• Published: Wiley, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Declined skeletal muscle mass and function are inevitable consequences of long‐term diabetes and bring about many adverse events. Muscle fibre atrophy and interstitial fibrosis are major pathological manifestations of diabetic sarcopenia. Stimulator of interferon genes (STING) pa...