A phase 2 trial of gemcitabine and docetaxel in patients with metastatic colorectal adenocarcinoma with methylated checkpoint with forkhead and ring finger domain promoter and/or microsatellite instability phenotype

Abstract We previously reported CHFR methylation in a subset of colorectal cancer (CRC; ∼30%) with high concordance with microsatellite instability (MSI). We also showed that CHFR methylation predicted for sensitivity to docetaxel, whereas the MSI‐high phenotypes were sensitive to gemcitabine. We hy...

Fuld beskrivelse

Saved in:
Bibliografiske detaljer
Main Authors: Marina Baretti (Author), Enusha Karunasena (Author), Marianna Zahurak (Author), Rosalind Walker (Author), Yang Zhao (Author), Thomas R. Pisanic 2nd (Author), Tza‐Huei Wang (Author), Tim F. Greten (Author), Austin G. Duffy (Author), Elske Gootjes (Author), Gerrit Meijer (Author), Henk M.W. Verheul (Author), Nita Ahuja (Author), James G. Herman (Author), Nilofer S. Azad (Author)
Format: Bog
Udgivet: Wiley, 2021-05-01T00:00:00Z.
Fag:
Online adgang:Connect to this object online.
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Internet

Connect to this object online.

3rd Floor Main Library

Detaljer om beholdninger fra 3rd Floor Main Library
Klassifikationsnummer: A1234.567
Kopi 1 Tilgængelig