Engineering and Purification of Microcin C7 Variants Resistant to Trypsin and Analysis of Their Biological Activity

• Main Authors: Guangxin Yang (Author), Lijun Shang (Author), Lu Liu (Author), Zeqiang Li (Author), Xiangfang Zeng (Author), Xiuliang Ding (Author), Jinxiu Huang (Author), Shiyan Qiao (Author), Haitao Yu (Author)
• Format: Book
• Published: MDPI AG, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Microcin C7 (McC) as a viable form of antimicrobial has gained substantial attention due to its distinctive antimicrobial activity, by targeting aspartyl tRNA synthetase. McC can be a potential solution against pathogenic microbial infections in the postantibiotic era. However, considering that degr...