Macrophage Migration Inhibitory Factor (MIF) and Thyroid Hormone Alterations in Antineutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis (AAV)

• Main Authors: Mårten Wendt (Author), Ola Börjesson (Author), Aune Avik (Author), Johan Bratt (Author), Björn Anderstam (Author), Abdul R. Qureshi (Author), Edmund J. Miller (Author), Iva Gunnarsson (Author), Annette Bruchfeld (Author)
• Format: Book
• Published: BMC, 2013-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine known to be released from lymphocytes, macrophages and endothelial cells and also in animal models shown to be inducible with glucocorticoids (GC). In contrast, thyroxine seems to antagonize MIF activity. To investig...