Suppression of Choroidal Neovascularization by AAV-Based Dual-Acting Antiangiogenic Gene Therapy

• Hauptverfasser: Anne Louise Askou (Verfasst von), Sidsel Alsing (Verfasst von), Josephine N.E. Benckendorff (Verfasst von), Andreas Holmgaard (Verfasst von), Jacob Giehm Mikkelsen (Verfasst von), Lars Aagaard (Verfasst von), Toke Bek (Verfasst von), Thomas J. Corydon (Verfasst von)
• Format: Buch
• Veröffentlicht: Elsevier, 2019-06-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Vascular endothelial growth factor A (VEGFA) is involved in the pathogenesis of vasoproliferative retinal diseases, such as exudative age-related macular degeneration (AMD). The objective of this study was to investigate whether dual-acting therapy based on the simultaneous expression of anti-VEGFA...