Design and analysis of stably integrated reporters for inducible transgene expression in human T cells and CAR NK-cell lines
Abstract Background Cytotoxic activity of T- and NK-cells can be efficiently retargeted against cancer cells using chimeric antigen receptors (CARs) and rTCRs. In the context of solid cancers, use of armored CAR T- and NK cells secreting additional anti-cancer molecules such as cytokines, chemokines...
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| Main Authors: | , , , , , , , , |
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| Format: | Book |
| Published: |
BMC,
2019-03-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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