Identification of Novel Arachidonic Acid 15-Lipoxygenase Inhibitors Based on the Bayesian Classifier Model and Computer-Aided High-Throughput Virtual Screening

• 主要な著者: Yinglin Liao (著者), Peng Cao (著者), Lianxiang Luo (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2022-11-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Ferroptosis is an iron-dependent lipid peroxidative form of cell death that is distinct from apoptosis and necrosis. ALOX15, also known as arachidonic acid 15-lipoxygenase, promotes ferroptosis by converting intracellular unsaturated lipids into oxidized lipid intermediates and is an important ferro...