Immunoinformatic of novel self-amplifying mRNA vaccine lipid nanoparticle against SARS-CoV-2

• Hoofdauteurs: Turmidzi Fath (Auteur), Endang Winiati Bachtiar (Auteur), Gulimiran Alitongbieke (Auteur), Yutian Pan (Auteur), Yuanqing Hu (Auteur), Retno Widowati (Auteur)
• Formaat: Boek
• Gepubliceerd in: Wolters Kluwer Medknow Publications, 2024-05-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

We developed innovative self-amplifying mRNA (sa-mRNA) vaccine based on the derivative of S and Nsp3 proteins, which are considered crucial adhering to human host cells. We performed B-cell, Major histocompatibility complex (MHC) I, and II epitope which were merged with the KK and GPGPG linker. We a...