Lack of Gαi2 proteins in adipocytes attenuates diet-induced obesity

• Main Authors: Veronika Leiss (Author), Annika Schönsiegel (Author), Thorsten Gnad (Author), Johannes Kerner (Author), Jyotsna Kaur (Author), Tina Sartorius (Author), Jürgen Machann (Author), Fritz Schick (Author), Lutz Birnbaumer (Author), Hans-Ulrich Häring (Author), Alexander Pfeifer (Author), Bernd Nürnberg (Author)
• Format: Book
• Published: Elsevier, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: Typically, obesity results from an inappropriate balance between energy uptake from nutrient consumption and burning of calories, which leads to a pathological increase in fat mass. Obesity is a major cause of insulin resistance and diabetes. Inhibitory G proteins (Gαi) form a subfamily...