METTL3 Facilitates Oral Squamous Cell Carcinoma Tumorigenesis by Enhancing c-Myc Stability via YTHDF1-Mediated m6A Modification

• Main Authors: Wei Zhao (Author), Yameng Cui (Author), Lina Liu (Author), Xiaozhou Ma (Author), Xiaoqian Qi (Author), Yue Wang (Author), Zihao Liu (Author), Shiqing Ma (Author), Jingwen Liu (Author), Jie Wu (Author)
• Format: Book
• Published: Elsevier, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

N6-Methyladenosine (m6A) is the most common internal modification of eukaryotic messenger RNA (mRNA) that occurred on the N6 nitrogen of adenosine. However, the roles of m6A in oral squamous cell carcinoma (OSCC) are still elusive. Here, we investigate the function and mechanism of methyltransferase...