Improvement of the Antibacterial Activity of Phage Lysin-Derived Peptide P87 through Maximization of Physicochemical Properties and Assessment of Its Therapeutic Potential

Phage lysins are a promising alternative to common antibiotic chemotherapy. However, they have been regarded as less effective against Gram-negative pathogens unless engineered, e.g., by fusing them to antimicrobial peptides (AMPs). AMPs themselves pose an alternative to antibiotics. In this work, A...

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Main Authors: Roberto Vázquez (Author), Antonio Doménech-Sánchez (Author), Susana Ruiz (Author), Julio Sempere (Author), Jose Yuste (Author), Sebastián Albertí (Author), Pedro García (Author)
Format: Book
Published: MDPI AG, 2022-10-01T00:00:00Z.
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