Letrozole increases preantral follicle growth and decreases estradiol production without impairing follicle survival

• Main Authors: Fukiko Kasuga-Yamashita (Author), Tsuyoshi Baba (Author), Sachiko Nagao (Author), Yuya Fujibe (Author), Miyuki Morishita (Author), Yoshika Kuno (Author), Tasuku Mariya (Author), Hiroyuki Honnma (Author), Toshiaki Endo (Author), Tamotsu Kiya (Author), Tsuyoshi Saito (Author)
• Format: Book
• Published: BMC, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Letrozole has been reported to be effective in treating anovulation, preventing ovarian hyperstimulation syndrome (OHSS), and retrieving oocytes in breast cancer patients. However, the role and mechanism of letrozole in follicular development remain unclear. Results We treated mo...