Xanthohumol ameliorates Diet-Induced Liver Dysfunction via Farnesoid X Receptor-Dependent and Independent Signaling

• Main Authors: Ines L. Paraiso (Author), Thai Q. Tran (Author), Armando Alcazar Magana (Author), Payel Kundu (Author), Jaewoo Choi (Author), Claudia S. Maier (Author), Gerd Bobe (Author), Jacob Raber (Author), Chrissa Kioussi (Author), Jan F. Stevens (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The farnesoid X receptor (FXR) plays a critical role in the regulation of lipid and bile acid (BA) homeostasis. Hepatic FXR loss results in lipid and BA accumulation, and progression from hepatic steatosis to nonalcoholic steatohepatitis (NASH). This study aimed to evaluate the effects of xanthohumo...