Xanthohumol ameliorates Diet-Induced Liver Dysfunction via Farnesoid X Receptor-Dependent and Independent Signaling

• Главные авторы: Ines L. Paraiso (Автор), Thai Q. Tran (Автор), Armando Alcazar Magana (Автор), Payel Kundu (Автор), Jaewoo Choi (Автор), Claudia S. Maier (Автор), Gerd Bobe (Автор), Jacob Raber (Автор), Chrissa Kioussi (Автор), Jan F. Stevens (Автор)
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• Опубликовано: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Предметы: article
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The farnesoid X receptor (FXR) plays a critical role in the regulation of lipid and bile acid (BA) homeostasis. Hepatic FXR loss results in lipid and BA accumulation, and progression from hepatic steatosis to nonalcoholic steatohepatitis (NASH). This study aimed to evaluate the effects of xanthohumo...