Intratracheally Inhalable Nifedipine-Loaded Chitosan-PLGA Nanocomposites as a Promising Nanoplatform for Lung Targeting: Snowballed Protection <i>via</i> Regulation of TGF-β/β-Catenin Pathway in Bleomycin-Induced Pulmonary Fibrosis

• Main Authors: Mohammed H. Elkomy (Author), Rasha A. Khallaf (Author), Mohamed O. Mahmoud (Author), Raghda R. S. Hussein (Author), Asmaa M. El-Kalaawy (Author), Abdel-Razik H. (Author), Heba M. Aboud (Author)
• Format: Book
• Published: MDPI AG, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pulmonary fibrosis is a serious ailment that may progress to lung remodeling and demolition, where the key participants in its incidence are fibroblasts responding to growth factors and cellular calcium swinging. Calcium channel blockers, like nifedipine (NFD), may represent auspicious agents in pul...