Intratracheally Inhalable Nifedipine-Loaded Chitosan-PLGA Nanocomposites as a Promising Nanoplatform for Lung Targeting: Snowballed Protection <i>via</i> Regulation of TGF-β/β-Catenin Pathway in Bleomycin-Induced Pulmonary Fibrosis
Pulmonary fibrosis is a serious ailment that may progress to lung remodeling and demolition, where the key participants in its incidence are fibroblasts responding to growth factors and cellular calcium swinging. Calcium channel blockers, like nifedipine (NFD), may represent auspicious agents in pul...
Saved in:
Main Authors: | Mohammed H. Elkomy (Author), Rasha A. Khallaf (Author), Mohamed O. Mahmoud (Author), Raghda R. S. Hussein (Author), Asmaa M. El-Kalaawy (Author), Abdel-Razik H. (Author), Heba M. Aboud (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2021-11-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Formation and Physico-Chemical Evaluation of Nifedipine-hydroxypropyl-β-cyclodextrin and Nifedipine-methyl-β-cyclodextrin: The Development of Orodispersible Tablets
by: Emma Adriana Ozon, et al.
Published: (2022) -
Bilosomes as a promising nanoplatform for oral delivery of an alkaloid nutraceutical: improved pharmacokinetic profile and snowballed hypoglycemic effect in diabetic rats
by: Mohammed H. Elkomy, et al.
Published: (2022) -
Intratracheal Administration of Itraconazole-Loaded Hyaluronated Glycerosomes as a Promising Nanoplatform for the Treatment of Lung Cancer: Formulation, Physiochemical, and In Vivo Distribution
by: Sultan Aati, et al.
Published: (2024) -
PLGA-Gold Nanocomposite: Preparation and Biomedical Applications
by: Alaaldin M. Alkilany, et al.
Published: (2022) -
Immunoregulatory and Antimicrobial Activity of Bovine Neutrophil β-Defensin-5-Loaded PLGA Nanoparticles against <i>Mycobacterium bovis</i>
by: Zhengmin Liang, et al.
Published: (2020)