Brozopine Inhibits 15-LOX-2 Metabolism Pathway After Transient Focal Cerebral Ischemia in Rats and OGD/R-Induced Hypoxia Injury in PC12 Cells

The goal of this study was to elucidate the mechanisms of protection of Sodium (±)-5-bromo-2-(α-hydroxypentyl) benzoate (trade name: Brozopine, BZP) against cerebral ischemia in vivo and in vitro. To explore the protective effect of BZP on focal cerebral ischemia-reperfusion injury, we evaluated the...

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Main Authors: Yuan Gao (Author), Xinyu Cao (Author), Xiaojiao Zhang (Author), Yangjun Wang (Author), He Huang (Author), Yonggang Meng (Author), Junbiao Chang (Author)
Format: Book
Published: Frontiers Media S.A., 2020-02-01T00:00:00Z.
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