Molecular mechanism of the spider toxin κ-LhTx-I acting on the bacterial voltage-gated sodium channel NaChBac

• Asıl Yazarlar: Zhen Xiao (Yazar), Yaqi Li (Yazar), Piao Zhao (Yazar), Xiangyue Wu (Yazar), Guoqing Luo (Yazar), Shuijiao Peng (Yazar), Hongrong Liu (Yazar), Cheng Tang (Yazar), Zhonghua Liu (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The bacterial sodium channel NaChBac is the prokaryotic prototype for the eukaryotic NaV and CaV channels, which could be used as a relatively simple model to study their structure-function relationships. However, few modulators of NaChBac have been reported thus far, and the pharmacology of NaChBac...