The hookworm tissue inhibitor of metalloproteases (Ac-TMP-1) modifies dendritic cell function and induces generation of CD4 and CD8 suppressor T cells.

• Main Authors: Carmen Cuéllar (Author), Wenhui Wu (Author), Susana Mendez (Author)
• Format: Knjiga
• Izdano: Public Library of Science (PLoS), 2009-01-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Hookworm infection is a major cause of disease burden for humans. Recent studies have described hookworm-related immunosuppression in endemic populations and animal models. A Tissue Inhibitor of Metalloproteases (Ac-TMP-1) has been identified as one of the most abundant proteins released by the adul...