Human neutrophil peptide-1 (HNP-1): a new anti-leishmanial drug candidate.

• Main Authors: Sara Dabirian (Author), Yasaman Taslimi (Author), Farnaz Zahedifard (Author), Elham Gholami (Author), Fatemeh Doustdari (Author), Mahdieh Motamedirad (Author), Shohreh Khatami (Author), Kayhan Azadmanesh (Author), Susanne Nylen (Author), Sima Rafati (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The toxicity of available drugs for treatment of leishmaniasis, coupled with emerging drug resistance, make it urgent to find new therapies. Antimicrobial peptides (AMPs) have a strong broad-spectrum antimicrobial activity with distinctive modes of action and are considered as promising therapeutic...