An injectable signal-amplifying device elicits a specific immune response against malignant glioblastoma

• Main Authors: Qiujun Qiu (Author), Sunhui Chen (Author), Huining He (Author), Jixiang Chen (Author), Xinyi Ding (Author), Dongdong Wang (Author), Jiangang Yang (Author), Pengcheng Guo (Author), Yang Li (Author), Jisu Kim (Author), Jianyong Sheng (Author), Chao Gao (Author), Bo Yin (Author), Shihao Zheng (Author), Jianxin Wang (Author)
• Format: Book
• Published: Elsevier, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Despite exciting achievements with some malignancies, immunotherapy for hypoimmunogenic cancers, especially glioblastoma (GBM), remains a formidable clinical challenge. Poor immunogenicity and deficient immune infiltrates are two major limitations to an effective cancer-specific immune response. Her...