Sphingomyelin Synthase 1 (SMS1) Downregulation Is Associated With Sphingolipid Reprogramming and a Worse Prognosis in Melanoma

Sphingomyelin Synthase 1 (SMS1) Downregulation Is Associated With Sphingolipid Reprogramming and a Worse Prognosis in Melanoma

Sphingolipid (SL) metabolism alterations have been frequently reported in cancer including in melanoma, a bad-prognosis skin cancer. In normal cells, de novo synthesized ceramide is mainly converted to sphingomyelin (SM), the most abundant SL, by sphingomyelin synthase 1 (SMS1) and, albeit to a less...

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Main Authors: Fatima Bilal (Author), Anne Montfort (Author), Julia Gilhodes (Author), Virginie Garcia (Author), Joëlle Riond (Author), Stéphane Carpentier (Author), Thomas Filleron (Author), Céline Colacios (Author), Thierry Levade (Author), Ahmad Daher (Author), Nicolas Meyer (Author), Nathalie Andrieu-Abadie (Author), Bruno Ségui (Author)
Format: Book
Published: Frontiers Media S.A., 2019-04-01T00:00:00Z.
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3rd Floor Main Library

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