The BCAT1 CXXC Motif Provides Protection against ROS in Acute Myeloid Leukaemia Cells

The BCAT1 CXXC Motif Provides Protection against ROS in Acute Myeloid Leukaemia Cells

The cytosolic branched-chain aminotransferase (BCAT1) has received attention for its role in myeloid leukaemia development, where studies indicate metabolic adaptations due to BCAT1 up-regulation. BCAT1, like the mitochondria isoform (BCAT2), shares a conserved CXXC motif ~10 Å from the active site....

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Main Authors: James Hillier (Author), Gemma J. Allcott (Author), Laura A. Guest (Author), Wayne Heaselgrave (Author), Alex Tonks (Author), Myra E. Conway (Author), Amy L. Cherry (Author), Steven J. Coles (Author)
Format: Book
Published: MDPI AG, 2022-03-01T00:00:00Z.
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3rd Floor Main Library

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